Medscape - Diabetes dosing for Humulin R, Novolin R (insulin regular human), frequency-based adverse effects, comprehensive interactions, contraindications. Novolin R (Regular Human Insulin Injection [Recombinant DNA origin] United States Pharmacopeia) is a polypeptide hormone structurally identical to native. Mixing: Do not mix Novolin R with any insulin for intravenous use. Do The dosage and timing of Novolin R must be individualized (). •. Subcutaneous. A Novolin R vial in use can be kept unrefrigerated as long as it is kept as cool as possible and away from heat or sunlight. More severe episodes with coma, seizureor neurologic impairment can be treated with intramuscular or subcutaneous glucagon information totem intravenous glucose. Regular insulin is only part of a complete treatment program that may also include diet, exercise, weight control, regular blood sugar testing, and special medical care. Furthermore, counseling on contraception and pregnancy may be novalin r because of the problems that can occur in patients with diabetes during pregnancy. Before starting, gather all of the supplies that you will need to use for preparing and giving your insulin injection. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. Make sure you tell your doctor if you have any other medical problems, especially: Pharmacokinetics After single subcutaneous administration of 0. Talk to your healthcare provider if you have any questions. Insulin is injected under the skin. Diabetic ketoacidosis may develop if your body has too little insulin. Keep a list of your medicines with you to show all your healthcare providers when you get a new medicine. Lipodystrophy Long-term use of insulin, including Novolin R, can cause lipodystrophy at the site of repeated insulin injections. Thiazolidinediones are peroxisome proliferator-activated receptor PPAR -gamma agonists and can cause dose-related fluid retention, particularly when used in combination with insulin; fluid retention may lead to or exacerbate heart failure; monitor for signs and symptoms of heart failure, treat the patient accordingly, and consider discontinuing thiazolidinediones. Ask your doctor, pharmacist, or other health care provider how to store Novolin R. Potentiated by salicylates, MAOIs, alcohol, sulfa drugs, some ACE inhibitors, drugs that inhibit pancreatic function eg, octreotide , oral hypoglycemic agents, anabolic steroids, quinine, quinidine, alpha-adrenergic blocking agents. Novolin R is a man-made insulin recombinant DNA origin that is structurally identical to the insulin produced by the human pancreas that is used to control high blood sugar in patients with diabetes mellitus. Your physician has explained that you have diabetes and that your treatment involves injections of insulin or insulin therapy combined with an oral antidiabetic medicine. The onset of action of Novolin R, when administered intravenously, is more rapid in comparison to subcutaneous administration. You need to be prepared for these emergencies. Pediatric TOP Appropriate studies have not been performed on the relationship of age to the effects of insulin human regular in the pediatric population. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy.